Wednesday, February 6, 2013

2/6/13

1. Review H.W.
2. REEBOP LAB- day 2

H.W. Print 14.1 Notes and do these:
EVEN MORE PATTERNS OF INHERITANCE PRACTICE PROBLEMS (Sex Linked Inheritance Practice Problems)
Answer these questions on a separate sheet of paper.  Show your work!!!!!
1.     Colorblindness is a sex-linked, recessive disorder.  What are the probable offspring outcomes from a father who is colorblind and a mother who is homozygous normal vision? Show your work!
2.     Myopia (poor eyesight) is a sex-linked, recessive disorder found in Reebops.  What are the probably offspring outcomes from a father reebop who has normal eyesight and a mother reebop who was myopia.  Show your work with a punnett square!
3.     Duchenne Muscular Dystrophy is caused by a recessive allele located on the X chromosome.
a.     Draw a Punnett square that show how two unaffected people can have a child with muscular dystrophy.  Include the genotypic ratio and phenotypic ratio for the offspring. 
b.     Is the child with muscular dystrophy male or female?
c.     What is the probability that the couple's next child will have muscular dystrophy?
d.     What percentage of the couple's male children will probably have muscular dystrophy?
e.     What percentage of the couple's female children will probably have muscular dystrophy?
4.      Hypophosphatemia, a disorder that causes low phosphate levels in the body and can cause bowed legs, is caused by a dominant allele on the X chromosome.
a.     Using A to represent the allele for hypophosphatemia, draw a punnett square that shows the possible offspring from a woman with genotype XAXa and a man with genotype XAY.
b.     What percentages of the children have hypophosphatemia?
c.     Are males more likely to have the disorder than females? Explain.
d.     Draw a Punnett square that show the possible offspring of a woman with a normal phenotype and a man with hypophosphatemia. Include the genotypic and phenotypic ratios for the offspring.
e.     What percentages of the children have the disorder for this cross?
f.     What percentages of the male offspring have the disorder for this cross? Explain this result.
5.     Color-blindness is a sex-linked trait in humans.  Normal vision (XB) is dominant over colorblindness.  Achondroplasia (a type of dwarfism) is an autosomal disorder.  Achondroplasia is dominant (A) to average height (a), though if a zygote inherits two dominant alleles (AA) it dies at birth.  
a.     Complete a two-factor Punnett square to predict the offspring for a colorblind, male with achondroplasia (XbYAa) and a heterozygous normal vision female with achondroplasia (XBXbAa).  
b.     What is the probability that they will have a child that is colorblind and Achondroplasiac?  Don't forget to exclude offspring with AA genotypes
6.     What is the pattern of inheritance that is illustrated for questions #1-5?